This 4-day course is focused on presenting concepts related to the PK and PK/PD evaluation of therapeutic proteins.
It will introduce participants to basic principles in the pharmacokinetic and pharmacodynamic
evaluation of novel therapeutic proteins and will provide opportunities for hands-on PK and
PK/PD modeling and simulation examples relevant to protein drugs. Topics include target-mediated drug disposition, tissue and tumor penetration, interspecies scaling, first-in-human dose selection, immunogenicity, model-based drug development and drug-drug interactions.
It will introduce participants to basic principles in the pharmacokinetic and pharmacodynamic
evaluation of novel therapeutic proteins and will provide opportunities for hands-on PK and
PK/PD modeling and simulation examples relevant to protein drugs. Topics include target-mediated drug disposition, tissue and tumor penetration, interspecies scaling, first-in-human dose selection, immunogenicity, model-based drug development and drug-drug interactions.
